Study of direct current stimulation in normal subjects.

JRCT ID: jRCTs042220008

Registered date:25/04/2022

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Normal subjects
• Date of first enrollment: 25/04/2022
• Target sample size: 22
• Study type: Interventional
• Intervention(s): Brain stimulation by transcranical direct current stimulation.

Outcome(s)

• Primary Outcome: Motor Evoked potential (MEP)

Secondary Outcome

ipsilateral Silent Period (iSP)
Upper limb dexterity (peg task)

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: < 85age old
• Gender: Both

Include criteria

1) Japanese healthy applicants, gender doesn`t matter.
2) Over 20 years old and under 85 years old.
3) Right handed.
4) Those who can participate in the study on the specified date after obtaining informed consent.
5) Those whose written consent form for participation in this research can be obtained.

Exclude criteria

1)Pregnant, potentially pregnant, or breastfeeding person.
2)History of alcoholism or under treatment.
3)History of epilepsy or under treatment.
4)Taking antidepressants,antipsychotics,or hypnotic sedatives for long period.
5)History or current illness of psychiatric and neurological disorders affecting motor function or cognitive function.
6)History or current illness of motor dysfunction of the upper limb due to injury, dosease, deformation or deficient of muscles, bones, or joints.
7)Have serious complications inckuding liver dysfunction, renal
dysfunction and endocrine disorders.
8)Those with medical devices containing magnetic parts or electronic circuits (artificial heart valves, artificial joints, vascular stents, cardiac pacemakers, intracranial metals such as aneurysm clips and shunt tubes that require pressure adjustment, deep brain stimulators, etc.) embedded in the body or body surface (excluding dental fillings).
9)Previous surgeries opening the skull.
10)Those who have magnetic materials in the body or beneath the surface of the body.
11)Those who are judged to be inappropriate by the researchers for participatin the study.

Related Information

• Primary Sponsor: Hattori Noriaki