Pharmacokinetics and safety of tryptophan.

JRCT ID: jRCTs041220025

Registered date:31/05/2022

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: healthy volunteer
• Date of first enrollment: 31/05/2022
• Target sample size: 5
• Study type: Interventional
• Intervention(s): Tryptophan dosing

Outcome(s)

• Primary Outcome: Changes in blood concentrations of tryptophan and related metabolites
• Secondary Outcome: Safety

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

- Has provided written consent for participation
- Age 20 or greater at the time of consent

Exclude criteria

- Pregnant or possibly pregnant women
- Lactating women
- With a history of hypersensitivity to tryptophan supplements
- Taking medications that act on serotonergic nervons
- Presence or history of psychiatric disease
- Presence of serious hepatic or renal impairment
- Deemed ineligible for the study as determined by the principal investigator or a co-investigator

Related Information

• Primary Sponsor: Kondo Masashi