Measurement of Elasticity of Skeletal Muscle Using Continuous Shear Wave Elastography

JRCT ID: jRCTs032220472

Registered date:28/11/2022

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Not specified
• Date of first enrollment: 28/11/2022
• Target sample size: 75
• Study type: Interventional
• Intervention(s): Shear wave generation by a small vibrator

Outcome(s)

• Primary Outcome: Comparison of muscle elasticity (shear wave velocity) by continuous shear wave elastography before and after administration of muscle relaxants
• Secondary Outcome: Comparison between depth of muscle relaxation obtained by neuromuscular monitoring and muscle elasticity (shear wave velocity) by continuous shear wave elastography

Key inclusion & exclusion criteria

• Age minimum: >= 18age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1) 18 years of age or older
2) Patients scheduled to undergo orthopedic surgery under general anesthesia
3) Patients in good general condition with a PS (Performance Status) of 2 or less
4) Patients scheduled to undergo neuromuscular monitoring and receive a muscle relaxant (rocuronium bromide)
5) Patients who do not have a disease that causes muscle atrophy or degeneration at the site of measurement
6) Patients who have no history of neuropsychiatric disorders and are not currently receiving any medical treatment.
7) Patients who have given written consent to participate in this study

Exclude criteria

1) Pregnant patients
2) Patients with a history of hypersensitivity to any history of Rocuronium Bromide
3) Patients with myasthenia gravis or myasthenic syndrome who have a history of hypersensitivity to sugammadex sodium
4) Patients with a pacemaker
5) Other patients who are judged by the physician to be unsuitable for the treatment

Related Information

• Primary Sponsor: Shitara Hitoshi
• Secondary Sponsor: Chikuda Hirotaka