Effects of ascorbic acid in preventing of delirium in cardiovascular surgery patients.

JRCT ID: jRCTs031220690

Registered date:09/03/2023

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: cardic disease needed surgery
• Date of first enrollment: 09/03/2023
• Target sample size: 50
• Study type: Interventional
• Intervention(s): After induction of anaesthesia in the operating theatre, 500 mg of ascorbic acid is administered transvenously before the start of surgery. Thereafter, 500 mg is administered every six hours for eight doses (2 g/day).

Outcome(s)

• Primary Outcome: incidence of post operative delirium
• Secondary Outcome: duration of post operative delirium

Key inclusion & exclusion criteria

• Age minimum: >= 70age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

70years old and over
scheduled for elective cardiovascular surgery using cardiopulmonary bypass
Ability to understand and consent to a written explanation of the clinical research

• Exclude criteria: urgent surgery

Related Information

• Primary Sponsor: Iizuka Yusuke
• Source(s) of Monetary Support: MEXT KAKENHI