Examination of aroma inhalation effect on post oral surgery nausea

JRCT ID: jRCTs011210021

Registered date:16/07/2021

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Postoperative nausea
• Date of first enrollment: 16/07/2021
• Target sample size: 182
• Study type: Interventional
• Intervention(s): Inhale aroma essential oils (blends) of lavender, ginger and peppermint diluted to 1% at the time of postoperative nausea. The inhalation time is 2 minutes, followed by another 2 minutes of inhalation after assessment of nausea severity. The control group uses only purified water for similar inhalation.

Outcome(s)

• Primary Outcome: Amount of change in the severity of nausea with and without aroma essential oil at the time of postoperative nausea.
• Secondary Outcome: Antiemetics use rate, drug name and dose used, patient satisfaction, adverse events.

Key inclusion & exclusion criteria

• Age minimum: >= 20age old
• Age maximum: Not applicable
• Gender: Both

Include criteria

1. Patients scheduled to undergo oral surgery under general anesthesia at Surgical Center or Center for Oral Surgery of Hokkaido University Hospital
2. Age 20+
3. ASA physical status class 1 or 2
4. Written informed consent

Exclude criteria

1. Lack of judgment, such as intellectual disability
2. Allergy to the aroma essential oil
3. Olfactory disorder
4. Hemorrhagic diathesis
5. ICU management after general anesthesia
6. Scheduled to administer intraoperative antiemetic prophylaxis
7. Judged by the primary sponser to be inappropriate as research subjects

Related Information

• Primary Sponsor: Kamekura Nobuhito