PRP treatment combined with tendon repair for Achilles tendon rupture in athletes (PRP treatment for Achilles tendon rupture in athletes)

JRCT ID: jRCTc050210153

Registered date:14/01/2022

Basic Information

• Recruitment status: Recruiting
• Health condition(s) or Problem(s) studied: Achilles tendon rupture
• Date of first enrollment: 30/01/2023
• Target sample size: 20
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Tendon repair
PRP injection
Tendon biopsy

Outcome(s)

• Primary Outcome: rate of return to sports until 6 months after intervention

Secondary Outcome

Rate of return to sports until 3,12, and 24 months after intervention
Post-operative complications including tendon re-rupture or infection
Ankle range of motion, calf circumference, single heel-rise
Pre- and post-operative MRI findings (Achilles tendon length, shape, signal change)
JSSF score, ATRS

Key inclusion & exclusion criteria

• Age minimum: >= 16age old
• Age maximum: < 65age old
• Gender: Both

Include criteria

1.patients who is scheduled to receive operative treatmenf for Achilles tendon rupture
2.athletes
3.patients who is scheduled to receive early functional rehabilitation after operation
4.patients aged sixteen and over and patients aged under sixty-five

Exclude criteria

1.patients who received steroid therapy
2.re-rupture case
3.patients who previously received operative treatment of Achilles tendon
4.patients who could not receive MRI examination
5.patients who is judged unsuitable by investigator

Related Information

• Primary Sponsor: Yasuda Toshito