NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
JRCT ID: jRCT1041210089

Registered date:27/10/2021

Study of preoperative oral nutritional supplements after neoadjuvant chemotherapy in esophageal carcinoma

Basic Information

Recruitment status Recruiting
Health condition(s) or Problem(s) studiedEsophageal carcinoma
Date of first enrollment27/10/2021
Target sample size50
Countries of recruitment
Study typeInterventional
Intervention(s)preoperative oral intake of ENORAS Liquid for Enteral Use

Outcome(s)

Primary OutcomeThe factors mentioned below will be evaluated comparing with historical controls. perioperative nutrition indexes GPS: Glasgow Prognostic Score mGPS: modified GPS PNI: Prognostic Nutritional Index CONUT score: Controlling Nutritional Status Score NLR: Neutrophil Lymphocyte Ratio PLR: Platelet Lymphocyte Ratio LMR: Lymphocyte Monocyte Ratio CAR: CRP Albumin Ration Alb: Albumin CRP: C reactive Protein Ch-E: Cholinesterase T-cho: Total Cholesterol Body weight Body composition
Secondary OutcomeThe factors mentioned below will be evaluated comparing with historical controls. Postoperative pneumoniae Postoperative complications Postoperative hospital stays Oral dose of ENORAS liquid for enteral use Diarrhea

Key inclusion & exclusion criteria

Age minimum>= 20age old
Age maximumNot applicable
GenderBoth
Include criteria1. Patients who treated with neoadjuvant chemotherapy followed by esophagectomy for esophageal carcinoma. 2. Written informed consent.
Exclude criteria1. oral feeding difficulty. 2. Treated with enteral nutrition other than ENORAS liquid for enteral use. 3. History of treatment for esophageal carcinoma. 4. Planed to undergo two-stage operation. 5. Contraindicate for ENORAS liquid for enteral use. 6. Ineligible for the study at the physician's assessment.

Related Information

Contact

Public contact
Name Dai Shimizu
Address 65, Tsurumaisco, Showaku, Nagoya Aichi Japan 466-8550
Telephone +81-527442249
E-mail d-shimizu@med.nagoya-u.ac.jp
Affiliation Nagoya University Graduate School of Medicine
Scientific contact
Name Yasuhiro Kodera
Address 65, Tsurumaisco, Showaku, Nagoya Aichi Japan 466-8550
Telephone +81-527442249
E-mail ykodera@med.nagoya-u.ac.jp
Affiliation Nagoya University Graduate School of Medicine