JRCT ID: jRCT1041210089
Registered date:27/10/2021
Study of preoperative oral nutritional supplements after neoadjuvant chemotherapy in esophageal carcinoma
Basic Information
Recruitment status | Recruiting |
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Health condition(s) or Problem(s) studied | Esophageal carcinoma |
Date of first enrollment | 27/10/2021 |
Target sample size | 50 |
Countries of recruitment | |
Study type | Interventional |
Intervention(s) | preoperative oral intake of ENORAS Liquid for Enteral Use |
Outcome(s)
Primary Outcome | The factors mentioned below will be evaluated comparing with historical controls. perioperative nutrition indexes GPS: Glasgow Prognostic Score mGPS: modified GPS PNI: Prognostic Nutritional Index CONUT score: Controlling Nutritional Status Score NLR: Neutrophil Lymphocyte Ratio PLR: Platelet Lymphocyte Ratio LMR: Lymphocyte Monocyte Ratio CAR: CRP Albumin Ration Alb: Albumin CRP: C reactive Protein Ch-E: Cholinesterase T-cho: Total Cholesterol Body weight Body composition |
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Secondary Outcome | The factors mentioned below will be evaluated comparing with historical controls. Postoperative pneumoniae Postoperative complications Postoperative hospital stays Oral dose of ENORAS liquid for enteral use Diarrhea |
Key inclusion & exclusion criteria
Age minimum | >= 20age old |
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Age maximum | Not applicable |
Gender | Both |
Include criteria | 1. Patients who treated with neoadjuvant chemotherapy followed by esophagectomy for esophageal carcinoma. 2. Written informed consent. |
Exclude criteria | 1. oral feeding difficulty. 2. Treated with enteral nutrition other than ENORAS liquid for enteral use. 3. History of treatment for esophageal carcinoma. 4. Planed to undergo two-stage operation. 5. Contraindicate for ENORAS liquid for enteral use. 6. Ineligible for the study at the physician's assessment. |
Related Information
Primary Sponsor | Kodera Yasuhiro |
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Secondary Sponsor | |
Source(s) of Monetary Support | |
Secondary ID(s) |
Contact
Public contact | |
Name | Dai Shimizu |
Address | 65, Tsurumaisco, Showaku, Nagoya Aichi Japan 466-8550 |
Telephone | +81-527442249 |
d-shimizu@med.nagoya-u.ac.jp | |
Affiliation | Nagoya University Graduate School of Medicine |
Scientific contact | |
Name | Yasuhiro Kodera |
Address | 65, Tsurumaisco, Showaku, Nagoya Aichi Japan 466-8550 |
Telephone | +81-527442249 |
ykodera@med.nagoya-u.ac.jp | |
Affiliation | Nagoya University Graduate School of Medicine |