NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
JRCT ID: jRCT1011200026

Registered date:26/03/2021

Analgesic effects of ultrasound-guided maxillary nerve block and inferior alveolar nerve block for upper and lower orthognathic surgery

Basic Information

Recruitment status Recruiting
Health condition(s) or Problem(s) studiedvertical jaw deformities
Date of first enrollment11/03/2021
Target sample size40
Countries of recruitment
Study typeInterventional
Intervention(s)In the block group, bilateral ultrasound-guided maxillary and inferior alveolar nerve blocks are performed after induction of general anesthesia, and 5 mL each of 0.375% levobupivacaine is administered for a total of 20 mL.

Outcome(s)

Primary OutcomeThe number of times rescue analgesics are used in the 24 hours following the block.
Secondary OutcomeAfter the block (1, 5, 15, 30, 60 min), levobupivacaine blood level, NRS at/after return, intraoperative opioid (fentanyl, remifentanil) use, pre-/postoperative QoR-40 scores, time to first analgesic use after discharge, complications of nerve block (local anesthetic systemic toxicity, hematoma, local infection), respiratory complications in the first 24 hours after surgery

Key inclusion & exclusion criteria

Age minimum>= 16age old
Age maximumNot applicable
GenderBoth
Include criteriaover 16 years of age ASA-PS I to III undergoing upper and lower jaw plastic surgery
Exclude criteriaPatients who are allergic to the study drug, blood coagulation disorders, chronic opioid use, pregnancy, mental disorders, patients who were not extubated in the operating room after surgery for some reason, and other patients who, at the discretion of the physician in charge, are considered inappropriate for this study.

Related Information

Contact

Public contact
Name Sho Kumita
Address S1W16, Chuo-ku, Sapporo, Hokkaido Hokkaido Japan 060-8543
Telephone +81-11-688-9663
E-mail todonotumari@me.com
Affiliation Sapporo Medical University School of Medicine
Scientific contact
Name Michiaki Yamakage
Address S1W16, Chuo-ku, Sapporo, Hokkaido Hokkaido Japan 060-8543
Telephone +81-11-688-9663
E-mail michiaki_yamakage@icloud.com
Affiliation Sapporo Medical University School of Medicine