NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000052960

Registered date:01/12/2023

Clinical research on aggressive lipid lowering therapy after catheterization

Basic Information

Recruitment status Recruiting
Health condition(s) or Problem(s) studiedAcute coronary syndrome
Date of first enrollment2017/05/26
Target sample size50
Countries of recruitmentJapan
Study typeObservational
Intervention(s)

Outcome(s)

Primary OutcomeEvaluation of biomarker variability (LDL, MMP9, PTX3, hs-CRP, TNF-alpha, L-arginine/ADMA Ratio, PCSK9 assessed at emergency PCI, 2 weeks, and 32-40 weeks post PCI)
Secondary OutcomeEvaluation of vulnerable plaque (assessed by coronary angioscopy at 32-40 weeks post PCI) Inhibition of myocardial remodeling (evaluated by echocardiography within 48 hours and at 32-40 weeks post PCI)

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum100years-old
GenderMale and Female
Include criteria
Exclude criteriaPatients who are already receiving a drug of the same type or a drug already being used before enrollment in the study. Patients who are not taking statin Patients with LDL-C less than 100 mg/dL Patients with contraindications to statins requiring concomitant use Patients with a history of hypersensitivity to any component of the drug used Patients whom the attending physician deems inappropriate for participation in the study on medical grounds Patients who are pregnant, lactating, may be pregnant, or wish to become pregnant during the study period.

Related Information

Contact

public contact
Name Hiroyasu Uzui
Address 23-3 Shimoaizuki, Matsuoka Eiheiji-Cho, Yoshida-gun, Fukui 910-1193
Telephone +81-776-61-3111
E-mail huzui@u-fukui.ac.jp
Affiliation University of Fukui Department of Cardiovascular Medicine
scientific contact
Name Hiroyasu Uzui
Address 23-3 Shimoaizuki, Matsuoka Eiheiji-Cho, Yoshida-gun, Fukui
Telephone +81-776-61-3111
E-mail huzui@u-fukui.ac.jp
Affiliation University of Fukui Department of Cardiovascular Medicine