UMIN ID: UMIN000047964
Registered date:01/07/2022
Study for overcoming the severe infertility by new indole compound (MA-5)
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | infertility patients |
| Date of first enrollment | 2022/07/01 |
| Target sample size | 80 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | Using discarded sperm, effect of MA-5 exposure is evaluated for sperm function (kinetics and fertilization ability) and mitochondrial function (ART production), and it is compared with non-treated counterpart. |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 42years-old |
| Gender | Male |
| Include criteria | |
| Exclude criteria | Patient who has infection, such as hepatitis B virus, hepatitis C virus, Syphilis and HIV. Patient who has been registered to other clinical study. Patient who are using supplement drugs which affects mitochondrial function, such as Vit C&E, CoQ10 etc. Sample may not be used if the sperm parameter is not enough to analyze, even if patient eligible to enter this study and agreed. |
Related Information
| Primary Sponsor | Tohoku university hospital |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | JSPS KAKENHI |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Masahito Tachibana |
| Address | 1-1 Seiryomachi, Aoba-ward, Sendai, Miyagi, 980-8574 Japan Japan 9808574 |
| Telephone | 0227177254 |
| masahito.tachibana.c1@tohoku.ac.jp | |
| Affiliation | Tohoku university hospital Dept of OB/GYN |
| scientific contact | |
| Name | Masahito Tachibana |
| Address | 1-1 Seiryomachi, Aoba-ward, Sendai, Miyagi, 980-8574 Japan Japan |
| Telephone | 0227177254 |
| masahito.tachibana.c1@tohoku.ac.jp | |
| Affiliation | Tohoku university graduate school of medicine Department of perinatology |