Analysis of the effect of carbon dioxide exposure on daytime sleepiness using multiple sleep latency test

UMIN ID: UMIN000045478

Registered date:14/09/2021

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: Sleeping disorder
• Date of first enrollment: 2021/10/01
• Target sample size: 25
• Countries of recruitment: Japan
• Study type: Interventional

Intervention(s)

Exposure to air for 30 min, 4 times
Exposure to 5,000 ppm CO2 for 30 min, 4 times

Outcome(s)

• Primary Outcome: Sleep latency in multiple sleep latency test, subjective sleepiness, and objective sleepiness

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: 35years-old
• Gender: Male
• Exclude criteria: Sleeping less than 6 hours for 4 or more days as a result of controlled bedtime/wake activity and activity meter sleep recording (7 days) before the study Subjects who consumed caffeine or alcohol on the day before the experiment Subjects who slept less than 6 hours on the day before the experiment. Subjects who showed "signs" of sleep disorder in the all-night polysomnography.

Related Information

• Primary Sponsor: Tohoku University
• Source(s) of Monetary Support: Tohoku University