NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
UMIN ID: UMIN000041875

Registered date:28/02/2021

A phase II study of Simultaneous integrated boost intensity modulated radiotherapy using volumetric modulated arc therapy for locally advanced lung cancers and thoracic malignancies

Basic Information

Recruitment status Complete: follow-up continuing
Health condition(s) or Problem(s) studiedLocally advanced non-small cell lung cancer, post-operative recurrence of non-small cell lung cancer
Date of first enrollment2016/02/06
Target sample size50
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)Patients recieved SIB-IMRT using VMAT, and total dose was 69Gy and 51Gy in 30 fractions for gross tumor and elective lymph node.

Outcome(s)

Primary Outcomeoverall survival rate at three years after radiation therapy
Secondary Outcomethe progression free survival at three years after radiation therapy, the incidence and degree of radiation pneumonitis, relationship between radiation pneumonitis and dosimetric factors the incidence of adverse effects the validity of re-treatment planning using the DIR software, the validity of adoptive radiation therapy with cone beam CT, determining the optimal re-planning period, the influence of the changes of body contour for the accuracy of IMRT

Key inclusion & exclusion criteria

Age minimumNot applicable
Age maximumNot applicable
GenderMale and Female
Include criteria
Exclude criteria1) history of thoracic irradiation 2) with uncontrollable co-morbidity 3) with other active double primary cancer 4) with interstitial pneumonitis or pulmonary fibrosis 5) in pregnant

Related Information

Contact

public contact
Name Masayuki Fujiwara
Address 1-1 Mukogawa-cho, Nshinomiya, Hyogo, Japan Japan 663-8501
Telephone 0798-45-6362
E-mail m-fuji@hyo-med.ac.jp
Affiliation Hyogo College of Medicine Department of Radiology
scientific contact
Name Koichiro Yamakado
Address 1-1 Mukogawa-cho, Nshinomiya, Hyogo, Japan Japan
Telephone 0798-45-6362
E-mail ko-yamakado@hyo-med.ac.jp
Affiliation Hyogo College of Medicine Department of Radiology