UMIN ID: UMIN000041875
Registered date:28/02/2021
A phase II study of Simultaneous integrated boost intensity modulated radiotherapy using volumetric modulated arc therapy for locally advanced lung cancers and thoracic malignancies
Basic Information
Recruitment status | Complete: follow-up continuing |
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Health condition(s) or Problem(s) studied | Locally advanced non-small cell lung cancer, post-operative recurrence of non-small cell lung cancer |
Date of first enrollment | 2016/02/06 |
Target sample size | 50 |
Countries of recruitment | Japan |
Study type | Interventional |
Intervention(s) | Patients recieved SIB-IMRT using VMAT, and total dose was 69Gy and 51Gy in 30 fractions for gross tumor and elective lymph node. |
Outcome(s)
Primary Outcome | overall survival rate at three years after radiation therapy |
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Secondary Outcome | the progression free survival at three years after radiation therapy, the incidence and degree of radiation pneumonitis, relationship between radiation pneumonitis and dosimetric factors the incidence of adverse effects the validity of re-treatment planning using the DIR software, the validity of adoptive radiation therapy with cone beam CT, determining the optimal re-planning period, the influence of the changes of body contour for the accuracy of IMRT |
Key inclusion & exclusion criteria
Age minimum | Not applicable |
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Age maximum | Not applicable |
Gender | Male and Female |
Include criteria | |
Exclude criteria | 1) history of thoracic irradiation 2) with uncontrollable co-morbidity 3) with other active double primary cancer 4) with interstitial pneumonitis or pulmonary fibrosis 5) in pregnant |
Related Information
Primary Sponsor | Hyogo College of Medicine |
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Secondary Sponsor | |
Source(s) of Monetary Support | none |
Secondary ID(s) |
Contact
public contact | |
Name | Masayuki Fujiwara |
Address | 1-1 Mukogawa-cho, Nshinomiya, Hyogo, Japan Japan 663-8501 |
Telephone | 0798-45-6362 |
m-fuji@hyo-med.ac.jp | |
Affiliation | Hyogo College of Medicine Department of Radiology |
scientific contact | |
Name | Koichiro Yamakado |
Address | 1-1 Mukogawa-cho, Nshinomiya, Hyogo, Japan Japan |
Telephone | 0798-45-6362 |
ko-yamakado@hyo-med.ac.jp | |
Affiliation | Hyogo College of Medicine Department of Radiology |