Changes in trace substances in peripheral blood following electroconvulsive therapy in patients with depression: a longitudinal observational study

UMIN ID: UMIN000024374

Registered date:17/10/2016

Basic Information

• Recruitment status: Complete: follow-up complete
• Health condition(s) or Problem(s) studied: 1. Inpatients with major depressive disorder 2. Healthy controls.
• Date of first enrollment: 2016/10/18
• Target sample size: 60
• Countries of recruitment: Japan
• Study type: Observational

Outcome(s)

• Primary Outcome: Changes in trace substances in peripheral blood following electroconvulsive therapy.

Key inclusion & exclusion criteria

• Age minimum: 20years-old
• Age maximum: Not applicable
• Gender: Male and Female
• Exclude criteria: [Patients with depression] 1) Presence of unstable physical illness. 2) History of electroconvulsive therapy for the past 6 months. 3) History of alcohol or any substance abuse for the past 6 months. 4) History of head trauma accompanied with severe neurological aftereffects. 5) History of vagal reflex induced by blood draw. [Healthy controls] 1) Presence of unstable physical illness. 2) History of vagal reflex induced by blood draw. 3) Those who are involved in this research. 4) Those who are exposed to potential pressure from investigators.

Related Information

• Primary Sponsor: Department of Neuropsychiatry, Keio University, School of Medicine
• Source(s) of Monetary Support: Department of Neuropsychiatry, Keio University, School of Medicine