UMIN ID: UMIN000019115
Registered date:25/09/2015
Pathophysiological roles of atherosclerotic carotid plaque phenotypes and bioactive substances in patients undergoing carotid endarterectomy
Basic Information
| Recruitment status | Complete: follow-up continuing |
|---|---|
| Health condition(s) or Problem(s) studied | 1. Atherosclerosis 2. Stroke 3. Carotid stenosis 4. Diabetes |
| Date of first enrollment | 2011/03/01 |
| Target sample size | 30 |
| Countries of recruitment | Japan |
| Study type | Observational |
| Intervention(s) |
Outcome(s)
| Primary Outcome | inflammatory mediators IL-6,IL-10,TNFalfa,MCP-1 activation/inflammatory markers in plaque and peripheral blood monocytes MHC-II, CD86, Dectin-1, CD206, CD16, CD68 |
|---|---|
| Secondary Outcome | body weight,BMI,waist circumference,blood pressure,HbA1c,FPG,TC,TG,LDL-C,HDL-C, UA,BUN,Cre |
Key inclusion & exclusion criteria
| Age minimum | 20years-old |
|---|---|
| Age maximum | 80years-old |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | 1. Subjects who have been determined to be unsuitable for the attending physician |
Related Information
| Primary Sponsor | National Hospital Organization, Kyoto Medical Center |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | National Hospital Organization, Kyoto Medical Center |
| Secondary ID(s) |
Contact
| public contact | |
| Name | Noriko Satoh-Asahara |
| Address | 1-1 Mukaihata-cho,Fukakusa,Fushimi-ku,Kyoto Japan |
| Telephone | 075-641-9161 |
| nsato@kyotolan.hosp.go.jp | |
| Affiliation | National Hospital Organization, Kyoto Medical Center Clinical Research Institute |
| scientific contact | |
| Name | Noriko Satoh-Asahara |
| Address | 1-1 Mukaihata-cho,Fukakusa,Fushimi-ku,Kyoto Japan |
| Telephone | 075-645-9161 |
| nsato@kyotolan.hosp.go.jp | |
| Affiliation | National Hospital Organization, Kyoto Medical Center Clinical Research Institute |