UMIN ID: UMIN000001997
Registered date:22/05/2009
Effects of pioglitazone or metformin on bone markers and bone mineral density as well as parameters of atherosclerosis in patients with type 2 diabetes
Basic Information
| Recruitment status | Complete: follow-up complete |
|---|---|
| Health condition(s) or Problem(s) studied | Type 2 diabetes mellitus |
| Date of first enrollment | 2006/11/01 |
| Target sample size | 60 |
| Countries of recruitment | Japan |
| Study type | Interventional |
| Intervention(s) | Pioglitazone Metformin |
Outcome(s)
| Primary Outcome | bone turnover marker, bone mineral density, intima-media thickness, pulse wave velocity |
|---|---|
| Secondary Outcome |
Key inclusion & exclusion criteria
| Age minimum | Not applicable |
|---|---|
| Age maximum | Not applicable |
| Gender | Male and Female |
| Include criteria | |
| Exclude criteria | Nobody had hepatic or renal dysfunction or nutritional derangements. Patients treated with TZDs and metformin were excluded from this study. All patients were free of drugs known to influence bone and calcium metabolism, such as vitamin D, bisphosphonate, or estrogen, up until the time of the study. |
Related Information
| Primary Sponsor | Department of Internal Medicine 1, Shimane University School of Medicine |
|---|---|
| Secondary Sponsor | |
| Source(s) of Monetary Support | Self funding |
| Secondary ID(s) |
Contact
| public contact | |
| Name | |
| Address | Japan |
| Telephone | |
| ippei.k@med.shimane-u.ac.jp | |
| Affiliation | Shimane University School of Medicine ternal Medicine 1 |
| scientific contact | |
| Name | Ippei Kanazawa |
| Address | 89-1 Enya-cho, Izumo, Shimane Japan |
| Telephone | |
| Affiliation | Shimane University School of Medicine Internal Medicine 1 |