UMIN ID: UMIN000000767
Registered date:01/04/2010
Phase-I/IIa study of radiofrequency ablation combined with in situ application of immunoadjuvant, Cal-TUMP
Basic Information
Recruitment status | Complete: follow-up complete |
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Health condition(s) or Problem(s) studied | Hepatocellular carcinoma |
Date of first enrollment | 2007/04/01 |
Target sample size | 16 |
Countries of recruitment | Japan |
Study type | Interventional |
Intervention(s) | Adjuvant |
Outcome(s)
Primary Outcome | Safety |
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Secondary Outcome |
Key inclusion & exclusion criteria
Age minimum | 18years-old |
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Age maximum | 80years-old |
Gender | Male and Female |
Include criteria | |
Exclude criteria | Exclusion criteria 1) Past history of other caner except hepatocellular carcinoma in recent 5 year, or present affecting cancer 2) Past history of autoimmune disease or present affecting autoimmune disease 3) Infected HIV 4) Technically difficult main tumor for radiofrequency ablation 5) Difficult for this treatment because of hematological disease or bleeding tendency 6) Uncontrolled diseases such as sever infectious disease, severe cardiac disease and psychological diseases 7) (1) Systemic administration of anti-cancer drugs or steroid, (2) Radiological or biological treatment which may affect to systemic condition, within 4 weeks before this treatment 8) Pregnant or nursing woman or person who has the possibility of pregnancy and plan to pregnant 9)Affecting tuberculosis, or more than 2 cm in diameter induration reaction positive after skin reaction test using immune adjuvant specially made in our hospital 10) inadequate cases by principle doctor including uncertainty to adherent to treatment protocol |
Related Information
Primary Sponsor | Kanazawa university |
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Secondary Sponsor | Kasumigaura Hospital Tokyo Medical University |
Source(s) of Monetary Support | Kanazawa university,Cell Medicine Co. Ltd |
Secondary ID(s) |
Contact
public contact | |
Name | |
Address | Japan |
Telephone | |
s-kaneko@umin.ac.jp | |
Affiliation | Kanazawa university University hospital |
scientific contact | |
Name | Shuichi Kaneko |
Address | Takara-machi, Kanazawa, Ishikawa, Japan Japan |
Telephone | |
Affiliation | Kanazawa university Graduate school of medicine |