NIPH Clinical Trials Search

UMIN ID: UMIN000000560

Registered date:01/01/2007

Phase II trial of dosetaxel and carboplatin as neoadjuvant chemotherapy in patients with stage Ib2-II nonsquamous cell carcinoma of uterine cervix

Basic Information

Recruitment status Complete: follow-up complete
Health condition(s) or Problem(s) studiednonsquamous cell carcinoma of uterine cervix
Date of first enrollment2006/12/01
Target sample size60
Countries of recruitmentJapan
Study typeInterventional
Intervention(s)patients with stage Ib2 or II with diameter of over 2 cm nonsquamous cell carcinoma of uterine cervix


Primary OutcomeEfficacy
Secondary OutcomeSafety

Key inclusion & exclusion criteria

Age minimum20years-old
Age maximum75years-old
Include criteria
Exclude criteria1 fever with over 38.0C 2 infection or WBC>12,000/mm3 3 severe complications 4 neuropathy >Grade 2 5 edema > Grade 2 6 double cancer 7 pleural effusion and ascites for which drainage are necessary. 8 previous chemotherapy by taxane compounds

Related Information


public contact
Name Muneaki Shimada
Address 36-1 Nishimachi, Yonago Japan Japan 683-8504
Telephone 0859-38-6647
Affiliation Tottori University Department of Obstetrics and Gynecology
scientific contact
Name Junzo Kigawa
Address 32-1 Noshiro-cho, Matsue, Shimane Japan
Telephone 0852-60-8000
Affiliation Matsue city hospital Department of Obstetrics and Gynecology