NIPH Clinical Trials Search

JAPANESE
国立保健医療科学院
JMACCT ID: JMA-IIA00077

Registered date:06/01/2012

Efficacy of Enamel Matrix Derivative/ Freeze-Dried Bone Allograft VS Enamel Matrix Derivative/ Demineralized Freeze-Dried Bone Allograft with or without Forced Eruption Treating Infrabony Defects: Two Randomized Trials

Basic Information

Recruitment status Other
Health condition(s) or Problem(s) studiedChronoc periodontitis
Date of first enrollment01/04/2004
Target sample size69
Countries of recruitmentJapan
Study typeOBSERVATIONAL
Intervention(s)Intervention type:DRUG. Intervention1:EMD alone vs EMD/FDBA vs EMD/DFDBA with or without forced eruption, Dose form:NOT APPLICABLE, Route of administration:NOT APPLICABLE ., Dose form:OTHER, Route of administration:NOT APPLICABLE Control intervention1:EMD alone without graft material (negative control) with or without forced eruption, Dose form:OTHER.

Outcome(s)

Primary OutcomeThe primary outcome measurewas absolute change in PD reduction and CAL gain from baseline to 1-year and 3 years follow-up.. Timepoint:1 year and 3 years follow-up.
Secondary OutcomeOPAL gain from baseline to 6 month . Timepoint: 6 months reentry surgery.

Key inclusion & exclusion criteria

Age minimumNo Limit
Age maximumNo Limit
GenderBOTH
Include criteria6mm>CAL and radiographic bone loss
Exclude criteria1) systematic diseases influencing periodontal surgery; 2) systematic medications affecting periodontal status; 3) pregnancy or lactation; 4) smoker; 5) sensitivity to minocycline and tetracycline.

Related Information

Contact

public contact
Name Shigeki Ogihara DDS,Ph.D.
Address Periodontics,7-16, Adachi 3 chome, Adachi-ku, Tokyo
Telephone +81-3-3849-8483
E-mail oshigeki@fantasy.plala.or.jp
Affiliation Ogihara Dental Clinic/ Periodontics &Implat Dentistry
scientific contact
Name Shigeki Ogihara DDS,Ph.D.
Address Periodontics,7-16, Adachi 3 chome, Adachi-ku, Tokyo
Telephone +81-3-3849-8483
E-mail
Affiliation Ogihara Dental Clinic/ Periodontics &Implat Dentistry